原发性肝癌导向治疗研究在肿瘤导向研究中具有重要地位。肝癌是导向治疗进入临床试验的较早对象,积累的临床经验最多,探索的面亦较广。文献中所用“载体”除抗铁蛋白抗体外,还有抗甲胎蛋白抗体,抗人肝癌抗体,抗癌胚抗原抗体,抗乙型肝炎表面抗原抗体以及碘油等。所用“弹头”目前仍以放射性核素为主,且已 The research on the targeted treatment of primary liver cancer plays an important role in tumor-oriented research. Liver cancer is the earliest target of targeted therapy for clinical trials, with the most accumulated clinical experience and broader exploration. The “carriers” used in the literature include anti-ferritin antibodies, anti-alpha-fetoprotein antibodies, anti-human liver cancer antibodies, anti-carcinoembryonic antigen antibodies, anti-hepatitis B surface antigen antibodies, and lipiodol. The “warheads” used are still mainly radionuclides and have