嗜铬细胞瘤的瘤细胞一般阵发性或持续性分泌多量肾上腺素和去甲肾上腺素,临床上呈阵发性或持续性高血压及代谢紊乱症群,常产生儿茶酚胺心肌病的严重症状,还可发生其它一些急症情况。如能早期诊断予以手术治疗,90％以上可以根愈。因此早期诊断很重要。尿VMA又称4-羟基-3-甲氧基-苦杏仁酸(HMMA),是肾上腺素和去甲肾上腺素最重要的最终代谢产物。临床上用于筛选嗜铬细胞瘤。测定尿中VMA的方法甚多,以分光光度计法较 Pheochromocytoma tumor cells generally paroxysmal or persistent secretion of large amounts of epinephrine and norepinephrine, clinically paroxysmal or persistent hypertension and metabolic disorder group, often produce serious symptoms of catecholamine cardiomyopathy, Other emergency situations can occur. If early diagnosis can be surgically treated, more than 90% can be cured. So early diagnosis is very important. Urinary VMA, also known as 4-hydroxy-3-methoxy-mandelic acid (HMMA), is the most important final metabolite of epinephrine and norepinephrine. Clinically used for screening pheochromocytoma. There are many ways to determine VMA in urine to compare with spectrophotometer method