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目的探讨老年人(50岁以上)高尿酸血症与异常心电图及心血管疾病的相关性。方法对2007年1月——7月来我院体检的企业退休人员6275人进行血尿酸检测及静息12导联心电图检查。结果①高尿酸血症的患病率为20.27%。②高尿酸血症组心电图异常率高于血尿酸正常组,两组间存在差异有统计学意义(p<0.01)。③左室高电压、传导阻滞、心房纤颤异常率两组间存在统计学差异p<0.05或p<0.01),ST—T改变两组间无统计学差异(p<0.01)。④在高尿酸血症组,心电图异常率与血尿酸水平之间无统计学差异(p>0.05)。结论高尿酸血症与高血压、冠心病等心血管疾病关系密切,属高危因素。
Objective To investigate the relationship between hyperuricemia and abnormal electrocardiogram (ECG) and cardiovascular disease in the elderly (over 50 years old). Methods A total of 6275 retirees aged from January 2007 to July 2007 in our hospital were tested for serum uric acid and 12-lead resting electrocardiogram. Results ① The prevalence of hyperuricemia was 20.27%. ② The abnormal rate of electrocardiogram in hyperuricemia group was higher than that of normal group with serum uric acid, the difference between the two groups was statistically significant (p <0.01). ③ There was a significant difference between left ventricular high voltage, conduction block and atrial fibrillation rate in two groups (p <0.05 or p <0.01). There was no significant difference between ST-T and control groups (p <0.01). ④ In the group of hyperuricemia, there was no significant difference between the abnormal rate of ECG and serum uric acid (p> 0.05). Conclusions Hyperuricemia is closely related to cardiovascular diseases such as hypertension and coronary heart disease, which are risk factors.