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目的：检测肺癌和良性肺疾病患者ＢＡＬＦ的Ｃｕ、Ｚｎ值，探讨其与肺癌的相关性。方法：选择病理确诊病例６９例为观察对象，其中肺癌组３１例，肺良性病组３８例。常规支气管肺泡灌洗术取得标本，灌洗液为ＮＳ３０ｍＬ，回收率４０％～６０％；用原子吸收光谱法测定Ｃｕ、Ｚｎ，并与血液为对照。结果：肺癌组血Ｃｕ显著高于良性组，Ｐ＜０．００５；肺癌组Ｃｕ／Ｚｎ高于良性组，Ｐ＜０．０５。肺癌组ＢＡＬＦＣｕ、Ｚｎ均低于良性组，Ｐ分别＜０．００５及０．０５；ＢＡＬＦＣｕ／Ｚｎ二组差异无显著性。表明检测ＢＡＬＦＣｕ、Ｚｎ对肺癌诊断有一定意义。结论：检测ＢＡＬＦＣｕ、Ｚｎ值及Ｃｕ／Ｚｎ比值对肺癌诊断有价值
Objective: To detect the Cu, Zn values of BALF in patients with lung cancer and benign lung diseases, and to explore its correlation with lung cancer. Methods: 69 cases with pathological diagnosis were selected as observation objects, including 31 cases in lung cancer group and 38 cases in benign lung disease group. Routine bronchoalveolar lavage obtained specimens, lavage fluid NS30mL, the recovery rate of 40% to 60%; Determination of Cu, Zn by atomic absorption spectrometry, and compared with the blood. Results: The blood level of Cu in the lung cancer group was significantly higher than that in the benign group (P<0.005). The Cu/Zn level in the lung cancer group was higher than that in the benign group (P<0.05). BALFCu and Zn in lung cancer group were lower than those in benign group, P<0.005 and 0.05, respectively; BALFCu/Zn group had no significant difference. It shows that the detection of BALFCu, Zn has a certain significance for the diagnosis of lung cancer. Conclusion: Detection of BALF Cu, Zn value and Cu/Zn ratio are valuable for the diagnosis of lung cancer