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目的观察前列泰片对实验性前列腺炎病理模型的影响。方法应用消痔灵注射前列腺法建立前列腺炎症的动物模型,将SD大鼠随机分为前列泰片高、中、低剂量组、阳性对照组、阴性对照组及假手术组,根据炎症的轻重进行病理分级,并给予相应积分。结果前列泰片高、中、低剂量组及阳性对照组的前列腺炎症积分分别为0．727±1．679、1．167±1．801、2±2．216、2．583±3．204,与阴性对照组(4．636±2．378)比较差别有显著性意义(P<0．01、P<0．01、P<0．05、P<0．05)。结论前列泰片对实验性前列腺炎有显著的抑制作用。
Objective To observe the effect of Qianlietai tablet on pathological model of experimental prostatitis. Methods The animal model of prostatitis was established by injection of Xiaozhiling into prostate. The SD rats were randomly divided into high, medium and low dose Qianlietai tablets group, positive control group, negative control group and sham operation group, according to the severity of inflammation Pathological grade, and give the corresponding points. Results Prostate inflammation scores of high, medium and low dose group and positive control group of Qianlietai tablet were 0.727 ± 1.679,1.167 ± 1.801,2 ± 2.216,2.583 ± 3.204 , Which was significantly lower than that in the negative control group (4.636 ± 2.378) (P <0.01, P <0.01, P <0.05, P <0.05). Conclusions Qianlietai tablets have significant inhibitory effect on experimental prostatitis.