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药物过敏反应是临床各科常见的课题之一,尤其以过敏性休克类型反应最为严重。笔者查阅1931～1978年国内医药学期刊228种,获药物过敏反应病例9,553例,其中过敏性休克计1,286例,占13.46%,仅次于固定型药疹,居药物过敏反应各类型的第二位。死亡186例,占过敏性休克的14.46%。为引起广泛注意,综述如下: 一、致敏药物和发病例数表众所周知,致过敏性休克的药物种类繁多,国内已报告114种之多。其中以抗菌素类为最多,占78.54%(1010/1286),特别是青霉素发病率达60.11%(773/1286),居首位。链霉素次之,占14.23%(183/1286)。须强调指出的是:中草(成)药所致过敏反应中,
Drug allergy is one of the common subjects in clinical subjects, especially the type of allergic shock the most serious reaction. The author reviewed 228 domestic pharmaceutical journals from 1931 to 1978, obtaining 9,553 cases of drug allergy, including 1,286 cases of anaphylactic shock, accounting for 13.46%, second only to the fixed drug eruption, ranking the second in each type of drug allergy . 186 cases of death, accounting for 14.46% of anaphylactic shock. To attract wide attention, summarized as follows: First, the number of allergens and the incidence of cases As we all know, a wide range of drugs induced anaphylactic shock, as many as 114 kinds of domestic reports. Among them, antibiotics accounted for 78.54% (1010/1286), especially penicillin (60.11%, 773/1286). Followed by streptomycin, accounting for 14.23% (183/1286). It should be emphasized that: Chinese herbal medicine (into) drug-induced allergic reactions,