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为观察不同剂量的牛磺酸侧脑室灌注对家兔体温的影响。方法：实验将新西兰家兔分为４组，分别静脉注射ＥＴ和ＮＳ后侧脑室灌注牛磺酸和人工脑脊液，测定家兔的直肠温度。结果：家兔侧脑室灌注小剂量牛磺酸（００３ｍｍｏｌ／ｋｇ）后，可以明显降低ＥＴ引起的体温上升，但对正常体温没有影响；用大剂量牛磺酸（００６ｍｍｏｌ／ｋｇ）灌注侧脑室，不仅完全阻断家兔的ＥＴ性发热，而且可以使家兔的正常体温降低。结论：牛磺酸脑室灌注具有降低家兔ＥＴ性发热和正常体温的作用，其降温效应与给药剂量有关。
To observe the different doses of taurine lateral ventricle on rabbit body temperature. Methods: New Zealand rabbits were divided into 4 groups. After intracerebroventricular injection of taurine and artificial cerebrospinal fluid after intravenous injection of ET and NS respectively, the rectal temperature of rabbits was measured. Results: After intravenous injection of taurine (003 mmol / kg) into the lateral ventricle of rabbits, the increase of body temperature in ET-induced rabbits could be obviously reduced, but no effect on body temperature was observed. High dose taurine (0.06 mmol / Perfusion of the lateral ventricle, not only completely blocked the ET fever in rabbits, but also can reduce the normal body temperature in rabbits. Conclusion: Taurine intraventricular infusion has the effect of reducing ET fever and normal body temperature in rabbits, and its cooling effect is related to the dosage.