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用苔盼蓝、吖啶橙染色、电子显微镜及DNA凝胶电泳等方法进行VP-16对卵巢癌细胞株影响的研究，旨在探讨其杀死肿瘤细胞的作用机制。结果表明，VP-16能使卵巢癌细胞出现典型的凋亡，且表现出时间和浓度的依赖性，DNA电泳呈现梯形改变，证明VP-16可诱导卵巢癌细胞发生程序性死亡，从而达到杀伤肿瘤细胞的目的。
The effects of VP-16 on ovarian cancer cell lines were studied by trypan blue, acridine orange staining, electron microscopy and DNA gel electrophoresis, and the mechanism of action of VP-16 on killing tumor cells was explored. The results showed that VP-16 could induce apoptosis of ovarian cancer cells in a time-and concentration-dependent manner. DNA electrophoresis showed a trapezoid change. It was shown that VP-16 could induce apoptosis in ovarian cancer cells and kill The purpose of tumor cells.