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哈尔滨市医药工程技术研究开发中心本文采用 UV 分光光度法考察不同浓度乙醇为溶出介质和定时取样时间的选择,确定拉西地平片科学合理的溶出介质和取样时间,并证明含无水乙醇30%的溶出介质和30mln 取样,可保证实验的可靠性和准确性,溶出度均大于片剂标示量的80%。
In this paper, UV spectrophotometry was used to investigate the choice of different concentrations of ethanol as dissolution media and timing sampling time to determine the reasonable dissolution media and sampling time of lacidipine tablets, and to prove that ethanol containing 30% Of the dissolution medium and 30mln sampling, to ensure the reliability and accuracy of the experiment, dissolution were greater than 80% of the tablet labeled amount.