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目的：比较曲安西龙（ｔｒｉａｍｃｉｎｏｌｏｎｅ）与醋酸泼尼松（ｐｒｅｄｎｉｓｏｎｅ）治疗活动期系统性红斑狼疮（ＳＬＥ）的疗效。方法：５７例ＳＬＥ随机双盲分组，对照组服用醋酸泼尼松１ｍｇ·ｋｇ－１·ｄ－１，治疗组服用相当于醋酸泼尼松剂量的曲安西龙０．８ｍｇ·ｋｇ－１·ｄ－１观察４～６周。结果：两组药物总有效率均为７３．７％，但接受曲安西龙治疗组的体重增加和满月脸的副作用发生率低于醋酸泼尼松组。结论：两组药物治疗ＳＬＥ的疗效相似，但曲安西龙的副作用小于醋酸泼尼松。
Objective: To compare the efficacy of triamcinolone and prednisone in the treatment of active systemic lupus erythematosus (SLE). Methods: Fifty-seven patients with SLE were randomly divided into two groups. The control group received prednisone acetate 1 mg · kg-1 · d-1, while the treatment group received triamcinolone acetonide 0.8 mg · kg-1 · d -1 observed for 4 to 6 weeks. Results: The total effective rate was 73.7% in both groups, but the incidence of side effects of weight gain and full moon face in triamcinolone acetonide treatment group was lower than that in prednisone acetate group. CONCLUSIONS: The efficacy of the two drugs in treating SLE is similar, but triamcinolone has less side effects than prednisone acetate.