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目的探讨急性时相蛋白与小儿脓毒症预后及危重评分的关系。方法选入50例脓毒症患儿于入院1d检测急性时相蛋白。结果血清转铁蛋白、前白蛋白与危重评分呈正相关,血浆C反应蛋白与危重评分呈负相关,死亡组转铁蛋白较存活组明显降低,与存活组比较差异均具有统计学意义。结论急性时相蛋白中血清转铁蛋白、前白蛋白、血浆C反应蛋白与危重评分相关;可以反映病情危重程度。转铁蛋白与预后相关。
Objective To investigate the relationship between the acute phase protein and the prognosis and risk score of pediatric sepsis. Methods Fifty children with sepsis were enrolled in this study. Results Serum transferrin and prealbumin were positively correlated with the critical score. The plasma C-reactive protein was negatively correlated with the critical score. The transferrin in the death group was significantly lower than that in the survivor group, and the difference was statistically significant compared with the survival group. Conclusions Serum transferrin, prealbumin, and plasma C-reactive protein in acute phase protein are correlated with risk score, which can reflect the severity of disease. Transferrin is associated with prognosis.