原发性骨内癌(primaryintraosseouscarcinomaofjaws,PIOC)是原发于颌骨内的鳞状细胞癌[1],又名颌骨中心性癌,此瘤较少见,临床上无典型特征,要诊断它并不容易,常常会误诊为其它肿瘤如口腔鳞状细胞癌,棘皮瘤型造釉细胞瘤等。临床资料患者,女,60岁。半年前右下后牙区疼痛,未经治疗 Primary intraosseous carcinoma of the mouth (primary intraosseouscarcinomaofjaws, PIOC) is the primary squamous cell carcinoma of the jaw [1], also known as jaw central cancer, the tumor is rare, no typical clinical features to diagnose it Is not easy, often misdiagnosed as other tumors such as oral squamous cell carcinoma, acanthocytoma ameloblastoma and so on. Clinical data, female, 60 years old. Right lower back pain six months ago, untreated