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目的探讨逼尿肌过度活动对女性膀胱过度活动症(OAB)患者夜间排尿、尿急及尿失禁严重程度的影响。方法研究对象选取2013年1月至2014年12月收治女性OAB共150例,均行尿动力学指标检测;其中出现逼尿肌过度活动共93例,设为观察组;未出现逼尿肌过度活动共57例,设为对照组;比较两组患者最大自由尿流率(Qmax)、平均自由尿流率(Qmean)、残余尿量(PRV)、膀胱测压容积、初始尿意容量、最大逼尿肌压力(Pdetmax)和最大尿流率时逼尿肌压力(Pdet Qmax)及OAB评分等。结果观察组患者膀胱测压容积和初始尿意容量均明显低于对照组,差异具有统计学意义(P均<0.05);两组患者Qmax、Qmean、PRV、Pdetmax及Pdet Qmax指标水平比较差异无统计学意义(P均>0.05);观察组患者夜间排尿频率评分、尿急评分、急迫性尿失禁评分及OAB总评分均明显高于对照组,差异具有统计学意义(P均<0.05);两组患者白天排尿频率评分比较差异无统计学意义(P>0.05)。结论女性OAB患者合并逼尿肌过度活动可加重夜尿、尿急及尿失禁等临床症状;在实际治疗过程中应加强尿动力学指标检测,以早期发现并给予有效干预。
Objective To investigate the effects of detrusor overactivity on nocturnal micturition, urinary urgency and urinary incontinence in female patients with overactive bladder (OAB). Methods The subjects were selected from January 2013 to December 2014, a total of 150 female OAB patients were enrolled in urodynamic tests; in which there were 93 cases of detrusor over-activity, as the observation group; did not appear detrusor over A total of 57 patients were enrolled as the control group. The Qmax, Qmean, PRV, bladder volume, initial urinary volume, maximal pressure Pdetmax and Pdet Qmax and OAB scores at the maximal uroflow rate. Results The volume of bladder pressure and initial urinary volume in observation group were significantly lower than those in control group (all P <0.05). There was no significant difference in Qmax, Qmean, PRV, Pdetmax and Pdet Qmax between the two groups (P0.05); nighttime voiding frequency, urinary urgency score, urinary incontinence score and OAB total score in the observation group were significantly higher than those in the control group, the difference was statistically significant (P all <0.05); two There was no significant difference in frequency of urination during the day between the two groups (P> 0.05). Conclusions Female OAB patients with detrusor overactivity may aggravate the clinical symptoms such as nocturia, urinary urgency and urinary incontinence. During the actual treatment, urodynamic indexes should be detected to detect and give effective intervention in the early stage.