自从150年前Corrigan首次描述主动脉瓣关闭不全(以下简称主闭)以来,对慢性主闭的病理解剖、临床表现以及血流动力学特征已为临床医生熟悉.但是,择期对慢性主闭患者进行主动脉瓣替换术,至今仍是心脏病学中的一个难题.普遍认为应在病人发生不可逆性心肌功能不全之前,择期对慢性主闭患者进行手术治疗.虽然至今尚缺乏解决这一难题的单一参数,但运动试验可 Since Corrigan first described the aortic regurgitation (referred to as the “main closure”) 150 years ago for the first time, the pathological anatomy, clinical presentation, and hemodynamic characteristics of the chronic main closure have become familiar to clinicians, however, Aortic valve replacement is still a difficult problem in cardiology, and it is generally accepted that patients with chronic primary closed surgery should be treated electively before irreversible myocardial dysfunction occurs. Single parameter, but exercise test can be