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目的:分析宫颈癌扩散加权成像特征及与病理相关性。方法:选取100例宫颈癌患者为观察组,100例健康志愿者为对照组,均接受磁共振检查。观察组患者均行病理学检查,并测定微血管密度。观察宫颈癌磁共振特征,并分析其与病理相关性。结果:1.磁共振共确诊宫颈癌97例,诊断符合率为97.0%。与病理分期比较,磁共振分期正确84例,正确率为84%。2.观察组宫颈癌病变区ADC值平均为(0.893±0.098)s/mm2,显著低于对照组的(1.623±0.132)s/mm2,差异具有统计学意义(P<0.05)。病理分期Ⅲ、Ⅳ其病变ADC值及MVD值显著低于Ⅰ、Ⅱ期病变,差异具有统计学意义(P<0.05)。经pearson相关分析,宫颈癌ADC值与MVD值间呈显著负相关(r=-0.502,P=0.011)。结论:在宫颈癌的诊断中,磁共振具有很高应用价值。宫颈癌病变于扩散加权成像呈高信号,其ADC值显著低于正常宫颈组织,且与MVD呈显著负相关。
Objective: To analyze the characteristics of diffusion weighted imaging of cervical cancer and its correlation with pathology. Methods: 100 cases of cervical cancer patients were selected as the observation group and 100 healthy volunteers as the control group, all undergoing magnetic resonance imaging. The observation group patients underwent pathological examination, and determination of microvessel density. To observe the cervical cancer magnetic resonance characteristics, and analyze the pathological correlation. A total of 97 cases of cervical cancer diagnosed by MRI, the diagnostic coincidence rate was 97.0%. Compared with the pathological stage, the correct staging of magnetic resonance 84 cases, the correct rate was 84%. The average ADC value of cervical lesions in observation group was (0.893 ± 0.098) s / mm2, which was significantly lower than that in control group (1.623 ± 0.132) s / mm2, the difference was statistically significant (P <0.05). Pathological stage Ⅲ, Ⅳ lesion ADC value and MVD value was significantly lower than Ⅰ, Ⅱ disease, the difference was statistically significant (P <0.05). Pearson correlation analysis showed that there was a significant negative correlation between ADC and MVD (r = -0.502, P = 0.011). Conclusion: In the diagnosis of cervical cancer, magnetic resonance has a high value. Cervical cancer lesions showed high signal intensity in diffusion-weighted imaging, and the ADC value was significantly lower than that in normal cervical tissue, and was negatively correlated with MVD.