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一般认为,骨髓移植就其本质来说与造血干细胞移植是一致的,其中主要起作用的是造血干细胞。造血细胞移植是指骨髓、胚胎肝和周围血白细胞中造血干细胞移植而言。造血干细胞可分为多向性干细胞和定向性干细胞,多向性造血干细胞(CFU-S)进一步分化为红系定向干细胞(CFU-E)和粒系定向干细胞(CFU-C)等,造血干细胞经过干细胞池、增殖池、成熟池和功能池4个阶段,发展成为各种血液有形成份。 许多因素可以影响造血干细胞的增殖和分化。各种造血器官的基质细胞所建立的特殊局部环境-造
It is generally believed that bone marrow transplantation is essentially the same as hematopoietic stem cell transplantation, of which hematopoietic stem cells play a major role. Hematopoietic cell transplantation refers to the bone marrow, embryonic liver and peripheral blood leukocytes in terms of hematopoietic stem cell transplantation. Hematopoietic stem cells can be divided into multi-directional stem cells and directional stem cells, and multi-directional hematopoietic stem cells (CFU-S) are further differentiated into erythroid directional stem cells (CFU-E) and granulocyte directional stem cells After the stem cell pool, proliferation pool, mature pool and functional pool in four stages, the development of a variety of blood visible components. Many factors can affect the proliferation and differentiation of hematopoietic stem cells. A variety of hematopoietic organs of the stromal cells established by the special local environment - made