急性早幼粒细胞白血病(APL)是一种特殊类型的白血病,特异基因与染色体核型改变为其分子遗传学特征,FAB分型为AML-M3。其临床表现主要有严重出血倾向、发热、骨痛、白细胞异常增高等,病程凶险,早期死亡多因发生弥散性血管内凝血及颅内出血。而通常情况下,该类型白血病浸润组织和器官并不常见,初起合并心脏浸润则更为罕见。现将1例APL初起即合并有心功能不全、严 Acute promyelocytic leukemia (APL) is a special type of leukemia. The specific gene and chromosomal karyotype change to its molecular genetic characteristics. FAB typing is AML-M3. The main clinical manifestations of severe bleeding tendency, fever, bone pain, increased abnormal leukocyte, dangerous course of disease, early death due to diffuse intracranial coagulation and intracranial hemorrhage. Under normal circumstances, this type of leukemia infiltration of tissues and organs is not common, early combined with cardiac infiltration is even more rare. A case of early APL is now merged with cardiac insufficiency, strict