70例高脂血症病人采用三种口服甲硝唑给药方案治疗:(Ⅰ)0.6gtid×10d,n=10;(Ⅱ)0.4gtid×10d,n=20;(Ⅲ)0.2gtid×10d,n=40.三种方案甘油三酯下降总有效率为80.0%,65.0%及52.5%;胆固醇下降总有效率为80.0%,75.0%及57.5%.三种方案治疗后甘油三酯和胆固醇下降百分数为;甘油三酯为56.64%,38.7%及33.55%;胆固醇为34.56%,24.6%及21.81%.甲硝唑降甘油三酯和胆固醇作用快速、明显;甲硝唑剂量越大的方案,服药后不良反应越重. Seventy patients with hyperlipidemia were treated with three oral metronidazole regimens: (Ⅰ) 0.6gtid × 10d, n = 10; (Ⅱ) 0.4gtid × 10d, n = 20; , n = 40. The total effective rate of three schemes triglyceride reduction was 80.0%, 65.0% and 52.5%; the total effective rate of cholesterol decreased was 80.0%, 75.0% and 57.5% .Three kinds of programs after treatment triglycerides and cholesterol The percentage of decrease was: triglyceride was 56.64%, 38.7% and 33.55%, cholesterol was 34.56%, 24.6% and 21.81% .The metronidazole hypoglycemic triglyceride and cholesterol had a rapid and obvious effect. The larger the dose of metronidazole After taking the more serious adverse reactions.