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1996年8月～1998年11月笔者进行了黄连皮炎膏的研究工作,其中包括中医药处方研究,制剂研究及临床疗效观察等。现将有关研究及其临床疗效报告如下:1 黄连皮炎膏中医药处方研究 从1984年以来,笔者在皮肤科门诊工作中,研制了多种中草药粉末,供临床外用调剂使用。其中摸索出治疗皮炎、湿疹类皮肤病比较固定的配方,应用水调、油调、膏霜剂调搽。其中应用市售膏霜剂调搽具有不油腻、润肤、清热止痒等优点。但是应用霜剂凋药粉,剂型不稳定,易发酵、变霉、干缩。因此,为了满足临床需要,必须研究一种性能稳定,疗效可靠的治疗常见皮肤病外用膏霜剂。根据临床经验,反复查考古今文献,最终确定黄连、黄芩等为黄连皮炎膏处方。
From August 1996 to November 1998, the author carried out research on Huanglian dermatitis ointment, which included prescription study of traditional Chinese medicine, preparation research and observation of clinical efficacy. The relevant research and clinical curative effect are reported as follows: 1 Study on prescription of traditional Chinese medicine of Coptis dermatitis ointment Since 1984, the author has developed a variety of Chinese herbal medicine powders for external clinical use in the dermatology clinic work. Among them, formulating a formula that is relatively fixed for the treatment of dermatitis and eczema skin diseases, the use of water, oil, cream cream is used. Among them, the use of commercially available creams has the advantages of non-greasy, emollient, heat and itching. However, the use of cream wither powder, the dosage form is unstable, easy to ferment, mold, shrinkage. Therefore, in order to meet clinical needs, it is necessary to study a topical cream for the treatment of common skin diseases with stable performance and reliable efficacy. According to clinical experience, repeated inspections of archaeological and modern literature, and ultimately determine the Huanglian, Huangqi, etc. for the prescription of Huanglian dermatitis ointment.