一、临床资料　　我院1988～1998年间住院确诊的老年人全血细胞减少的巨幼细胞贫血20例,占同期收治的33例老年人巨幼细胞贫血的60%,其中男14例,女6例;年龄60～78岁,中位年龄65岁。病程1个月～1年,均符合巨幼细胞贫血的诊断标准〔1〕。20例均有乏力、头晕,口腔溃疡5例,黄疸1例, First, the clinical data of our hospital from 1988 to 1998 confirmed hospitalized elderly patients with pancytopenia, 20 cases of megaloblastic anemia, accounting for 33 cases of elderly treated megaloblastic anemia in 60%, of which 14 males and 6 females ; Aged 60 to 78 years old, the median age of 65 years. Duration of 1 month to 1 year, are in line with the diagnosis of megaloblastic anemia [1]. 20 cases were fatigue, dizziness, oral ulcers in 5 cases, 1 case of jaundice,