脑利钠肽(BNP)是一种主要从心室分泌的多肽类激素,在维持正常的心脏结构和功能中起着重要的代偿作用,其同源代谢产物N-末端脑利钠肽原(NT-proBNP)具有半衰期长、浓度高、稳定性良好等优点。临床测定血浆NT-proBNP水平可以客观、准确地评价心功能状况,可作为临床诊断心力衰竭的实验室指标,同时可用于对心力衰竭的疗效判断、预后评估及治疗指导。 Brain natriuretic peptide (BNP), a peptide hormone secreted mainly from the ventricles, plays an important compensatory role in maintaining normal cardiac structure and function. Its cognate metabolite, N-terminal pro-brain natriuretic peptide NT-proBNP) has the advantages of long half-life, high concentration, good stability and so on. The clinical determination of plasma NT-proBNP level can objectively and accurately evaluate cardiac function status, which can be used as a laboratory index for clinical diagnosis of heart failure. At the same time, it can be used to judge the curative effect of heart failure, prognosis evaluation and treatment guidance.