所谓生物碱类药物不能与碱性药物配伍,主要是指生物碱盐的水溶液不能与碱性药物配伍。生物碱与生物碱盐的药理作用虽然相同,但在理化性质方面有些不一样,如生物碱一般不溶于水或难溶于水(只有极少数例外,如咖啡因、麻黄碱等),能溶于乙醇、乙醚、氯仿等有机溶剂;而当生物碱与酸(如盐酸、硫酸等)结合成生物碱盐后, The so-called alkaloids drugs can not be compatible with alkaline drugs, mainly refers to the alkaloid salt solution can not be compatible with alkaline drugs. Although the pharmacological effects of alkaloids and alkaloids salts are the same, there are some differences in their physical and chemical properties. For example, alkaloids are generally insoluble or insoluble in water (with only a few exceptions such as caffeine and ephedrine) In ethanol, ether, chloroform and other organic solvents; and when alkaloids and acids (such as hydrochloric acid, sulfuric acid, etc.) combined into alkaloids salt,