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探讨慢性病毒性肝炎的分型及其诊断标准.方法将303例确诊CPH、CAH的肝脏病理改变以1995年病毒性肝炎防治方案的慢性肝炎分型(新方案)病理标准进行分级(G)、分期(S)、分度,结合病因、陆床分析。结果CPH、轻型CAH为新分型慢肝轻度G1G2,S0.2,中型CAH为中度G3、S1-3,重型CAH为重度G。、S2-4。TB、ALT与病理分级呈正相关(γ值均=1,P均=0.05),与病理分期无显著关系,ALB、A/G与病理分级、分期均呈负相关(γ值均=-1,P值=0.05及P值<0.05)。HBV合并HAV或HCV或HDV或HEV以中度、重度为高,分别为26.08%,29.41%。TB、ALT、ALB水平及A/G各型间有显著性差异(P值均<0.01),TB、ALT以重度最高,ALB、A/G以重度最低,其次为中度、轻度各项肝功异常率各型间均有显著性差异(P值均<0.05)。结论各项肝功异常率结合其异常水平对慢肝分型有诊断参考意义,新分型方案能更准确反映慢肝的病变进程及内在规律、有利于正确诊断及疗效考核,其分型标准待进一步完善,准确。
To investigate the classification of chronic viral hepatitis and its diagnostic criteria. Methods Pathological changes of liver cirrhosis (CPH and CAH) in 303 patients diagnosed by pathology were graded by grading (G), staging (S), indexing, combined with etiology, analysis. Results The CPH and light CAH were moderately slow G1G2 and moderate SAG2.2, medium and medium CAH were G3 and S1-3 respectively, and severe CAH was severe G. , S2-4. There was a positive correlation between TB, ALT and histopathological grade (all γ = 1, P = 0.05), but no significant correlation with pathological stage. ALB and A / G were negatively correlated with pathological grade and stage 1, P value = 0.05 and P value <0.05). HBV combined with HAV or HCV or HDV or HEV with moderate and severe high, respectively, 26.08%, 29.41%. The levels of TB, ALT, ALB and A / G were all significantly different (P <0.01), TB, ALT were the highest, ALB and A / G were the lowest, followed by moderate and mild All kinds of abnormal liver function rates were significantly different (P <0.05). Conclusions The abnormal rates of liver function combined with their abnormal levels have diagnostic significance for the classification of slow liver. The new classification scheme can reflect the process and internal rules of chronic liver more accurately, and is conducive to the correct diagnosis and therapeutic evaluation. The classification criteria To be further improved, accurate.