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目的探讨咽拭支原体快速镜检在诊断儿童支原体感染中临床意义。方法对139例支原体肺炎和113例非支原体肺炎患儿进行咽拭肺炎支原体快速镜检,并与血清学酶联免疫吸附试验(ELISA)法的敏感性及可靠性进行比较。结果支原体快速镜检法在灵敏度、阴性预测值、假阳性率方面低于ELISA法(P均<0.05);但前者在假阳性率方面则低于后者(P<0.05),两法联合应用,其灵敏度、阴性预测值、诊断符合率高于单用ELISA法(P<0.05),但特异度低于前者(P<0.01)。结论咽拭肺炎支原体快速镜检可及时明确诊断,便于治疗。两种检测方法对肺炎支原体检测各有优点,联合应用咽拭肺炎支原体快速镜检及ELISA法可提高敏感性。
Objective To investigate the clinical significance of rapid microscopic examination of Mycoplasma pharynx in the diagnosis of Mycoplasma infection in children. Methods 139 cases of mycoplasma pneumonia and 113 cases of children with non-mycoplasma pneumoniae Mycoplasma pneumoniae rapid microscopic examination and serum serological ELISA test for sensitivity and reliability were compared. Results Mycoplasma rapid microscopy was lower than ELISA in sensitivity, negative predictive value and false positive rate (P <0.05), but the former was lower than the latter in false positive rate (P <0.05) The sensitivity, negative predictive value and diagnostic coincidence rate were higher than the single ELISA (P <0.05), but the specificity was lower than the former (P <0.01). Conclusion Throat swab Mycoplasma pneumoniae rapid microscopic diagnosis can be promptly diagnosed, easy to treat. The two detection methods for Mycoplasma pneumoniae have their own advantages, combined with rapid detection of Mycoplasma pharyngeal swab and ELISA can improve the sensitivity.