论文部分内容阅读
提供了２Ｒ３Ｒ（＋）水飞蓟宾全合成的新方法．以取代的查尔酮为原料，经不对称环氧化、手性ＨＰＬＣ柱分离、立体选择性环合得光学纯的２Ｒ３Ｒ（＋）黄杉素，然后，与松柏醇经立体选择性氧化缩合得２Ｒ３Ｒ（＋）水飞蓟宾
Provides a new method for total synthesis of 2R3R (+) silybin. Using substituted chalcone as starting material, the optically pure 2R3R (+) taxol was stereoselectively cyclized by asymmetric epoxidation and separation by chiral HPLC, and then was stereoselectively oxidatively condensed with coniferyl alcohol Get 2R3R (+) silybin