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提供了2R3R(+)水飞蓟宾全合成的新方法.以取代的查尔酮为原料,经不对称环氧化、手性HPLC柱分离、立体选择性环合得光学纯的2R3R(+)黄杉素,然后,与松柏醇经立体选择性氧化缩合得2R3R(+)水飞蓟宾
Provides a new method for total synthesis of 2R3R (+) silybin. Using substituted chalcone as starting material, the optically pure 2R3R (+) taxol was stereoselectively cyclized by asymmetric epoxidation and separation by chiral HPLC, and then was stereoselectively oxidatively condensed with coniferyl alcohol Get 2R3R (+) silybin