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目的 探讨搏动性导管 (pulsatilecatheter,PUCA)泵在心脏复苏中的应用 ,为临床抢救心跳骤停的患者提供一种新的思路。方法 健康绵羊 11只 ,致室颤心脏停跳行心脏复苏 ,根据有无PUCA泵辅助及辅助是否及时分三组 :无辅助 (n =3)、延迟辅助 (n =2 )和即时辅助(n =6 ) ,记录并比较 3组复苏所持续时间和成败率。分别于复苏后 5min、 6 0min和 180min监测并记录血流动力学参数。结果 无辅助、延迟辅助和即时辅助复苏持续时间分别为 (38 3± 5 8)min、 (4 3 5± 9 2 )min和 (4 8 7± 2 3 8)min ,3组比较差异无显著性 (P >0 0 5 ) ;3组成败比分别为 0 / 3、 0 / 2和 5 / 1,差异有显著性 (P <0 0 5 )。复苏成功的 5只绵羊在支持期间血流动力学逐步恢复并趋向稳定 ,血压在辅助 180min与 5min相比有明显的统计学意义 (P<0 0 5 )。结论 心跳骤停中 ,在PUCA泵即时辅助下行心脏复苏明显提高复苏成功率 ,并能恢复和稳定复苏动物的血流动力学 ;该结果可望拓展PUCA泵在临床上新的应用
Objective To investigate the application of pulsatilecatheter (PUCA) pump in cardiopulmonary resuscitation and provide a new idea for clinical rescue of patients with cardiac arrest. Methods Eleven healthy rabbits were randomly divided into three groups according to the presence or absence of PUCA pump assist and assist: no assistance (n = 3), delayed assistance (n = 2) and immediate assistance = 6), record and compare the duration and success rate of the three groups resuscitation. The hemodynamic parameters were monitored and recorded at 5 min, 60 min and 180 min after resuscitation respectively. The duration of delayed and immediate adjuvant recovery was (38 3 ± 5 8) min, (4 3 5 ± 9 2) min and (4 8 7 ± 2 3 8) min, respectively, with no significant difference between the 3 groups (P> 0.05). The odds ratios of the three groups were 0/3, 0/2 and 5/1 respectively (P <0.05). Five sheep recovered successfully and their hemodynamics gradually recovered and tended to be stable. Blood pressure was significantly higher than that of 5 min after 180 min (P <0.05). Conclusions In cardiac arrest, immediate cardiac resuscitation with PUCA pump significantly improves the success rate of resuscitation and restores and stabilizes hemodynamics of resuscitative animals. This result is expected to expand the clinical application of PUCA pump