论文部分内容阅读
目的:分析急性下呼吸道感染患儿合并哮喘的危险因素。方法:选取2013-01-2015-06我院接受治疗的1 000例确诊为下呼吸道感染的患儿作为研究对象。将475例单纯下呼吸道感染患儿设为对照组,525例下呼吸道感染伴有哮喘的患儿设为观察组。主要研究危险因素分析,检查病原体,检测5项相关因素指标及胸片改变。结果:2组患儿年龄、性别、哮喘家族病史、过敏体质、既往诊断(哮喘、婴幼儿哮喘、咳嗽变异性哮喘、细支气管炎、肺炎)以及既往哮喘发生季节(春秋季)比较差异有统计学意义(P<0.05);多因素Logistic分析发现,急性下呼吸道感染患儿发生哮喘的危险因素为年龄、性别、哮喘家族病史、过敏体质、有既往相关疾病史及既往哮喘发生季节(春秋季);除了年龄与既往诊断和急性下呼吸道感染患儿发生哮喘呈负相关,而其余指标与急性下呼吸道感染患儿发生哮喘则呈正相关。2组患儿的C反应蛋白(CRP)、白细胞、嗜酸性粒细胞、中性粒细胞及IL-6水平比较差异有统计学意义(P<0.05);2组患儿的不同胸片的改变例数比较,差异有统计学意义(P<0.05)。结论:急性下呼吸道感染患儿合并哮喘的感染率高,其中存在影响较多的危险因素,应针对这些危险因素针对性预防控制。
Objective: To analyze the risk factors of asthma in children with acute lower respiratory tract infection. Methods: A total of 1 000 children diagnosed with lower respiratory tract infection in our hospital from January 2013 to June 2015 were selected as the study subjects. 475 cases of simple lower respiratory tract infection in children as the control group, 525 cases of lower respiratory tract infection with asthma in children as the observation group. The main study of risk factors analysis, check the pathogens, detection of 5 related factors and chest X-ray changes. Results: There were statistically significant differences in age, gender, family history of asthma, allergy, previous diagnosis (asthma, infant asthma, cough variant bronchitis, bronchiolitis, pneumonia) and past asthma season (P <0.05). Logistic analysis showed that the risk factors of asthma in children with acute lower respiratory tract infection were age, sex, family history of asthma, history of allergic diseases, history of previous related diseases and the occurrence of previous asthma (spring and autumn ); In addition to age and past diagnosis and acute lower respiratory tract infection in children with asthma was negatively correlated, while the remaining indicators of acute lower respiratory tract infection in children with asthma was positively correlated. There were significant differences in CRP, leucocyte, eosinophil, neutrophil and IL-6 between the two groups (P <0.05). The changes of different chest radiographs in two groups The number of cases were compared, the difference was statistically significant (P <0.05). Conclusions: The infection rate of asthma in children with acute lower respiratory tract infection is high, and there are more risk factors for them. The prevention and control of these risk factors should be targeted.