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目的探讨血浆Hcy水平与脑血管疾病之间的关系,从而为脑血管疾病的防治提供参考性意见。方法对本院2008年3月至2009年5月收治脑卒中患者59例进行回顾性分析,用酶联免疫法测定血浆Hcy。结果脑卒中组患者血浆Hcy显著高于对照组;脑梗死组和脑出血组患者血浆Hcy比较没有统计学差异;老年组与非老年组患者血浆Hcy比较无统计学差异;首发组患者血浆Hcy显著低于复发组。结论血Hcy水平增高是脑卒中危险因素之一,酶联免疫法准确性高,可用于基层医院及实验室血浆Hcy浓度的检测工作及大宗临床病例的筛查。
Objective To investigate the relationship between plasma Hcy levels and cerebrovascular diseases and to provide reference for the prevention and treatment of cerebrovascular diseases. Methods A retrospective analysis was performed on 59 patients with stroke admitted from March 2008 to May 2009 in our hospital. Plasma homocysteine level was determined by enzyme-linked immunosorbent assay. Results Plasma homocysteine level in stroke group was significantly higher than that in control group. There was no significant difference in plasma Hcy between cerebral infarction group and cerebral hemorrhage group. There was no significant difference in plasma Hcy between elderly group and non-elderly group. Lower than the recurrence group. Conclusions High blood Hcy level is one of the risk factors of stroke. ELISA is of high accuracy and can be used for the detection of plasma Hcy concentration in primary hospitals and laboratories and for the screening of bulk clinical cases.