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在抗病毒感染中,被感染细胞呈递内源性抗原被Tc细胞识别.曾破认为是激活Tc细胞反应的主要机制。本实验有力证明:非造血细胞产生抗病毒Tc细胞反应依赖MHC-1类分子的外源性抗原呈递作用。 抗原呈递相关转运体(TAP)是MHC-1类分子
In antiviral infections, infected cells present endogenous antigens recognized by Tc cells, which have been identified as the primary mechanism that activates Tc cell responses. This experiment has proved that: non-hematopoietic cells produce antiviral Tc cell response dependent on MHC-1 molecules exogenous antigen presentation. Antigen-presenting related transporters (TAPs) are MHC class-I molecules