单一动眼神经麻痹最常见于动脉瘤,血管性疾??病,外伤及肿瘤,而罕见于多发性硬化。作者报道一例以不全动眼神经麻痹为首发体征的多发性硬化。患者,男性,27岁,既往体健,其父患有多发性硬化,患者首先表现眼注视困难,五天后双眼视物模糊,次日,出现持续性右眼睑下垂,无其它症状。查单眼视力,色觉、视野均正常,瞳孔等大,光反射正常,右眼睑下垂5mm,右眼上视、内收受限,左眼运动自如,双眼底正常。右眉上区痛温觉轻度减弱,头颅CT平扫和增强及脑血管造影、血液、脑脊液检查均正常,静脉腾喜龙行重症肌无力试验阴性,一个月后,右眼睑下垂持续存在,四个月后 Single oculomotor nerve paralysis is most common in aneurysms, vascular disease, trauma and cancer, but rare in multiple sclerosis. The authors report a case of multiple sclerosis, which is initially characterized by suboptimal oculomotor palsy. Patient, male, 27 years old, former physical health, whose father has multiple sclerosis. The patient first showed difficulty in looking into the eye. After five days, the binocular vision was blurred. The next day, there was persistent right ptosis with no other symptoms. Check the monocular visual acuity, color vision, visual field are normal, pupil and other large, normal light reflex, right eyelid ptosis 5mm, right eye on the TV, adduction limited, left eye movement freely, both eyes normal. Right eyebrow area mild pain mild warming, cranial CT scan and enhancement and cerebral angiography, blood, cerebrospinal fluid were normal, intravenous Teng Sik Lung line myasthenia gravis test negative, a month later, the right eyelid ptosis persists, Four months later