贲门失弛缓症是以食管下括约肌松弛异常及食管体部缺乏推进性蠕动为特征的食管运动功能障碍。诸多研究表明,贲门失弛缓症的主要形态学特征为肠肌丛内神经节细胞减少或缺如。因这些形态学特征位于肠肌丛内,内镜活检过于表浅而无助于评估。失弛缓症患者的组 Cardiac achalasia is an esophageal motility disorder characterized by anomalous relaxation of the lower esophageal sphincter and lack of propulsive peristalsis in the esophageal body. Many studies have shown that the main morphological features of achalasia is reduced or absent of ganglion cells in the myenteric plexus. Because of these morphological features located in the myenteric plexus, endoscopic biopsy is too superficial to help assess. Group of achalasia patients