预激综合征在一般人群中的发病率为1.6％,预激综合征病人中12～60％出现阵发性室上性心动过速。文献曾报道在一个家庭中有多个成员患有预激综合征合并阵发性室上性心动过速;同样,也曾报道某些成员患有预激综合征,而另一些则患有阵发性室上性心动过速。本文报道4个家庭,一名成员患有预激综合征和阵发性室上性心动过速,并至少另有一名成员患有阵发性室上性心动过速。家庭1,患者于出生后10天首次发生室上性心动过速,每年发作的次数不等。13岁时,每月要发作数次。其父患预激综合征,常有阵发性室上性心动过速发作,于33岁时突然死亡。二个伯母常有室上性心动过速发作。1个堂姐患预激综合征合并阵发 Pre-excitation syndrome in the general population incidence of 1.6%, WPW syndrome in patients with 12 to 60% of paroxysmal supraventricular tachycardia. It has been reported in the literature that many members of a family have Wolff-Parkinson-White syndrome with paroxysmal supraventricular tachycardia; similarly, some members have been reported to have Wolff-Parkinson-White syndrome while others have a Paroxysmal supraventricular tachycardia. This article reports four families, one member with pre-excitation syndrome and paroxysmal supraventricular tachycardia, and at least one other member who has paroxysmal supraventricular tachycardia. Family 1, patients with first occurrence of supraventricular tachycardia 10 days after birth, the number of attacks each year varies. Thirteen years old, to attack several times a month. His father suffering from pre-excitation syndrome, often paroxysmal supraventricular tachycardia attack, died suddenly at the age of 33. Two aunt often have supraventricular tachycardia attack. A cousin pre-excitation syndrome with paroxysmal