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目的：研究止吐药应用的时间对镇痛泵使用患者止吐效果的影响。方法：选取57例镇痛泵使用患者作为研究对象，并随机分为3组，分别给予3组患者术前、术后使用昂丹司琼（术前组、术后组）、不使用昂丹司琼（对照组）。比较3组术后恶心呕吐（的发生率。结果：术前组和术后组的呕吐发生率（分别为42.11%、10.53%）均低于对照组（73.68%），而术前组和术后组比较，术后组的呕吐发生率更低，且P<0.05。结论：给予镇痛泵使用患者术后使用止吐药的止吐效果更佳。“,”Objective To study the time antiemetic applications using antiemetic effect of analgesia patients.Methods 57 cases before the use of analgesia in patients for the study, and were randomly divided into three groups, were given three groups of patients after surgery using ondansetron (preoperative group after group), do not use ondansetron Joan (the control group). Comparison of the three groups of postoperative nausea and vomiting (incidence.Results Preoperative group and the incidence of postoperative vomiting group (respectively 42.11%, 10.53%) were lower than in the control group (73.68%), while the preoperative and postoperative group group, a lower incidence of postoperative vomiting group and P <0.05.Conclusion The use of postoperative analgesia administered antiemetic use of antiemetic better.