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胰腺导管腺癌(PDAC)是一种恶性程度极高、早期难以诊断、预后极差的恶性肿瘤。近年来的研究发现肿瘤微环境及免疫调节与PDAC的发生密切相关,生物学微环境的研究可能为这种致死性癌症的治疗提供新的策略。笔者就PDAC肿瘤微环境研究的最新进展进行综述。
Pancreatic ductal adenocarcinoma (PDAC) is a malignant tumor with a very high degree of malignancy, which is difficult to diagnose early and whose prognosis is very poor. In recent years, the study found that tumor microenvironment and immune regulation are closely related to the occurrence of PDAC. The study of biological microenvironment may provide a new strategy for the treatment of this lethal cancer. The author reviews the latest progress of PDAC tumor microenvironment research.