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目的进行消化系统恶性肿瘤患者的生存分析,研究各项因素与该类患者生存时间的关联程度。方法对2008-2011年中国石油天然气集团公司中心医院普外科及肠道外科收治的368例消化系统恶性肿瘤患者进行随访调查、回顾性分析研究,计算生存期、生存率以及进行各项因素的关联研究等。结果因消化系统恶性肿瘤而死亡的病例中位生存期为10个月。1年累计生存率为46.7%,10年累计生存率为2.1%。Cox模型分析提示高龄是危险因素(OR=1.352);女性(OR=0.594)、进行手术治疗(OR=0.606)、较早出现疼痛症状(OR=0.620)则为保护因素。结论本研究显示消化系统恶性肿瘤患者的生存时间仍然较短;高龄是其独立危险因素,而女性、手术治疗、早期出现疼痛症状是保护因素,这些因素都有一定的可预测性,可为今后的临床工作起指导作用。
Objective To analyze the survival of patients with digestive system malignancies and investigate the relationship between various factors and the survival time of these patients. Methods A total of 368 patients with digestive system malignant tumors admitted to General Surgery Center of China National Petroleum Corporation from January to August 2008 were enrolled in this study. The data were analyzed retrospectively, and the survival rates, survival rates and the associations of various factors were analyzed retrospectively Research and so on. Results The median survival of patients who died of digestive system malignancies was 10 months. The 1-year cumulative survival rate was 46.7% and the 10-year cumulative survival rate was 2.1%. Cox model analysis indicated that elderly patients were risk factors (OR = 1.352); women (OR = 0.594) were treated by surgery (OR = 0.606). Earlier pain symptoms (OR = 0.620) were protective factors. Conclusion This study shows that survival time of patients with digestive system malignant tumors is still relatively short. Elderly is an independent risk factor. Female, surgical treatment and early symptoms of pain are protective factors. These factors are predictable for future Clinical work as a guide.