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目的研究全子宫切除术后阴道菌群及pH的变化,寻求适当的治疗措施,以提高术后患者的生活质量。方法分别观察术后未发生阴道炎、发生老年性阴道炎及正常近龄妇女3组共90例,进行菌群分析、pH测定,并使用乳杆菌DM9811代谢物脂肪酸组分对发生老年性阴道炎者进行治疗。结果术后妇女检出各种菌的数量少,乳杆菌的数量更少,阴道内没有占绝对优势的菌种;发生阴道炎组乳杆菌数量下降更明显,葡萄球菌及大肠埃希菌数量相对增多。术后阴道pH在5.9~7.3,发生阴道炎组较未发生阴道炎组高;以乳杆菌DM9811代谢物脂肪酸组分阴道用药治疗老年性阴道炎,治愈率为82.14%。结论全子宫切除术后阴道乳杆菌数量下降,pH升高,易发生老年性阴道炎。治疗以乳杆菌DM9811代谢物脂肪酸组分阴道用药效果佳。
Objective To study the changes of vaginal flora and pH after total hysterectomy and seek appropriate treatment measures to improve the quality of life of postoperative patients. Methods 90 cases of vaginitis, senile vaginitis and normal age women were observed in the three groups. The results of microbiological analysis, pH measurement and fatty acid composition of Lactobacillus DM9811 were used to evaluate the incidence of senile vaginitis For treatment. Results Postoperative women detected a small number of various bacteria, the number of lactobacilli less, no absolute dominant vaginal bacteria; occurrence of vaginitis Lactobacillus more obvious decline in the number of Staphylococcus aureus and Escherichia coli relative increase. Vaginal pH was 5.9 ~ 7.3 after operation, vaginitis was higher in patients with vaginitis than in patients without vaginitis. Vaginal administration of Lactobacillus DM9811 fatty acid was used vaginally to treat senile vaginitis. The cure rate was 82.14%. Conclusion The total number of vaginal lactobacilli after hysterectomy decreased, pH increased, prone to senile vaginitis. Treatment with Lactobacillus DM9811 metabolites fatty acid component vaginal medication good effect.