功能性高分子的主链选用壳聚糖,利用西弗碱反应制备了癸基化壳聚糖与具有亲疏水性质的羧甲基化癸基化壳聚糖衍生物。通过疏水相互作用,制备了壳聚糖负载氧化铁复合纳米粒子,复合粒子为超顺磁性,分散良好,尺寸均一,性质稳定,生物相容性好。 Chitosan was selected as the main chain of the functional polymer, and decylated chitosan and carboxymethylated decylated chitosan derivatives with hydrophilicity and hydrophobicity were prepared by the reaction of Severine. Through the hydrophobic interaction, chitosan-loaded iron oxide composite nanoparticles were prepared. The composite particles were superparamagnetic with good dispersion, uniform size, stable properties and good biocompatibility.