论文部分内容阅读
近年来,有关共刺激分子在免疫调节中的作用已经越来越受到广大研究者重视。已知协同刺激分子分为3个家族:B7家族、TNF家族和细胞因子家族。B7家族作为惟一能从抗原提呈细胞(antigen presenting cell,APC)单向传送信号至T细胞的共刺激分子,其正向的共刺激分子是以CD28为代表,而负向的共刺激分子已成为目前研究的热点,其中共刺激分子
In recent years, the role of costimulatory molecules in immune regulation has been paid more and more attention by researchers. It is known that costimulatory molecules are divided into three families: the B7 family, the TNF family and the cytokine family. The B7 family, as the only costimulatory molecule that can deliver signals from antigen presenting cell (APC) unidirectionally to T cells, has a positive costimulatory molecule represented by CD28 and a negative costimulatory molecule Become a hot research point, which co-stimuli