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本文用细胞内微注射法对不同强度的脉冲磁场对细胞缝隙连接通讯 (GJIC)功能的效应进行了研究 ,并与正弦磁场的作用以及脉冲磁场所感生的不同电场的作用进行了比较和探索。研究发现 0 .41mT以上强度的脉冲磁场具有抑制GJIC的作用 ,这种作用与磁场强度有关。其抑制GJIC的效应比正弦磁场为强。经相同磁场不同强度感应电场作用的比较 ,得出 ,GJIC的抑制主要由磁场引起 ,而与感应电场关系不大。本文首次从研究对GJIC的作用提供了脉冲磁场治疗创伤愈合等有关理论依据
In this paper, the effect of pulse magnetic field of different intensities on the function of GJIC was studied by intracellular microinjection, and the effect of sinusoidal magnetic field and different electric fields induced by pulsed magnetic field were compared and explored. It is found that the pulsed magnetic field above 0 .41 mT has the effect of inhibiting GJIC, which is related to the strength of the magnetic field. The effect of suppressing GJIC is stronger than the sinusoidal magnetic field. The comparison of the action of different electric field induced by the same magnetic field shows that the suppression of GJIC is mainly caused by the magnetic field but not by the induced electric field. This article for the first time from the study of the role of GJIC provides a theoretical basis for the pulse magnetic field treatment of wound healing