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目的探讨慢性肺源性心脏病电解质紊乱的治疗方法以及观察其预后状态。方法选取永煤集团总医院于2009年1月至10月的120例慢性肺源性心脏病电解质紊乱的患者,将研究对象随机分成A、B两组,每组60例。A组给予精氨酸、纳洛酮进行治疗,B组不给予精氨酸、纳洛酮治疗。观察两组的疗效,观察期为1年。结果 60例电解质紊乱的慢性肺源性心脏病患者在酸碱平衡失调后给予精氨酸、纳洛酮进行治疗,大部分都能将氧分压、二氧化碳分压以及凝血酶原时间恢复到接近正常的状态,且指标在治疗后与治疗前相比差异均具有统计学意义。结论采用精氨酸、纳洛酮对慢性肺源性心脏病合并电解质紊乱进行治疗,能够得到比不进行此项治疗更好的预后。精氨酸、纳洛酮对慢性肺源性心脏病,呼吸衰竭合并低钾、低钠、低氯血症的治疗作用,疗效高,效果非常显著,不良反应少。
Objective To investigate the treatment of electrolyte imbalance in chronic cor pulmonale and to observe its prognosis. Methods A total of 120 patients with chronic cor pulmonale with electrolyte imbalance of heart disease from January 2009 to October 2009 in Yongmei Group General Hospital were enrolled. The subjects were randomly divided into A and B groups, 60 cases in each group. Group A was treated with arginine and naloxone, and group B was given arginine and naloxone. Observed the curative effect of two groups, observation period was 1 year. Results Sixty patients with electrolyte-deficient chronic cor pulmonale were treated with arginine and naloxone after acid-base imbalance, and most of them recovered the partial pressure of oxygen, partial pressure of carbon dioxide and prothrombin time Normal state, and the indicators after treatment compared with before treatment were statistically significant differences. Conclusions Arginine and naloxone are effective in treating patients with chronic cor pulmonale complicated with electrolyte imbalance, which is better than that without this treatment. Arginine and naloxone have the therapeutic effect on chronic pulmonary heart disease and respiratory failure combined with hypokalemia, hyponatremia and hypochlorosis. The curative effect is high, the effect is very remarkable and the adverse reactions are few.