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慢性乙型肝炎 (简称慢乙肝 )常伴有肠源性内毒素血症(ＩＥＴＭ )。脂多糖 (ＬＰＳ )与其在单核 /巨噬细胞表面受体ＣＤ14的结合 ,可诱导在单核 /巨噬细胞表面分泌、释放ＴＮＦ α,进而加重肝细胞的损害。脂多糖结合蛋白 (ＬＢＰ )影响并调节ＬＰＳ与ＣＤ14的结合及对肝细胞的毒
Chronic hepatitis B (referred to as chronic hepatitis B) often accompanied by intestinal endotoxemia (IETM). The binding of lipopolysaccharide (LPS) to its receptor CD14 on the monocyte / macrophage surface induces secretion on the surface of monocytes / macrophages and releases TNF-alpha, which further aggravates hepatocyte damage. Lipopolysaccharide binding protein (LBP) affects and regulates LPS binding to CD14 and hepatotoxicity