抗生素从青霉素正式生产和临床使用至今已有五十年的历史了。目前从自然界微生物中发现和分离到的抗生素已有6500种,制备的半合成抗生素化合物近10万个。世界抗生素产量近3万吨,临床使用的抗生素180多种,抗生素早已成为临床广泛使用的重要的化疗药品之一。 我国大规模的开展抗生素研究始于五十年代,六十年代初期抗生素的许多品种在我国已能大量生产并得到广泛的应用。近年我国抗生素的产量近万吨,研制成功和临床应用品种近百种,在保障我国人民健康和农畜牧业方面也起到了一定的作用。 多年来我国有关抗生素的论著多零散的发表在微生物学、药学刊物上,1976年四川抗菌素工业研究所情报室在所领导和全所科技人员的支持下创办了《抗生素》杂志,十年 Antibiotics from penicillin formal production and clinical use has been 50 years of history. At present, there are 6,500 antibiotics found and isolated from microorganisms in nature, and about 100,000 semi-synthetic antibiotic compounds have been prepared. Nearly 30,000 tons of antibiotics are produced in the world and more than 180 kinds of antibiotics are used clinically. Antibiotics have long been one of the important chemotherapy drugs widely used clinically. China started a large-scale antibiotic research began in the fifties, many antibiotics in the early sixties in many varieties have been able to mass production and has been widely used. In recent years, the production of antibiotics in our country has reached nearly 10,000 tons. There are nearly 100 species successfully developed and clinically applied, and they have also played a certain role in safeguarding people’s health and animal husbandry in our country. Over the years, many articles about antibiotics in China were published in many microbiology and pharmacy journals. In 1976, the Intelligence Room of the Sichuan Institute of Antibiotics Industry founded the magazine “Antibiotics” with the support of all the science and technology personnel and the ten-year