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国际丙型肝炎病毒(HCV)及其感染学术会议于1993年6月28日～7月1日在土耳其伊斯坦布尔举行。到会各国代表400余人,我国有1名代表。大会共宣读论文39篇,墙报展示148篇,另有综述报告12篇。内容涉及HCV基因的克隆、表达与分类,HCV预防疫苗的研制,HCV的免疫学与病理学,HCV检测诊断,丙型肝炎流行病学及特异治疗等。现将主要进展介绍如下。一、HCV基因表达调控与分型 HCV基因组一级结构已经清楚:全长约9.5Kb,由5′-NCR、C、E_1、E_2/NS_1、NS_2、NS_3、NS_4和NS_5及3′-NCR等9个功能区组成。目前世界上有近10个国家(包括我国)成功
The International Symposium on Hepatitis C Virus (HCV) and Its Infections was held in Istanbul, Turkey from June 28 to July 1, 1993. There will be more than 400 delegates from all countries and one representative from our country. The conference read a total of 39 papers, wall posters 148, and another review report 12. It covers the cloning, expression and classification of HCV genes, the development of HCV vaccines, the immunology and pathology of HCV, the detection and diagnosis of HCV, the epidemiology and specific treatment of hepatitis C, and so on. The main progress is introduced below. First, the regulation of HCV gene expression and classification of HCV genome has been clearly defined: the total length of about 9.5Kb, from 5’-NCR, C, E_1, E_2 / NS_1, NS_2, NS_3, NS_4 and NS_5 and 3’-NCR 9 functional areas. At present, nearly 10 countries in the world, including our country, have succeeded