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乙型肝炎病毒(HBV)感染是目前世界范围内威胁人类健康的一个重要问题。本文简述HBxAg在HBV感染中的表达、HBxAg是HBV基因骗码的一种转录激活因子、HBxAg的转录激活作用及其激活的靶序列、细胞转录因子在HBxAg激活过程中的作用以及HBxAg改变细胞转录因子活性的机理。
Hepatitis B virus (HBV) infection is currently an important issue that threatens human health around the world. This article briefly describes the expression of HBxAg in HBV infection. HBxAg is a transcriptional activator of HBV gene, the transcriptional activation of HBxAg and its activation target, the role of transcription factors in HBxAg activation and HBxAg-altering cells Mechanism of transcription factor activity.