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目的运用联合检测的方法,研究血清胱抑素C联合尿白蛋白肌酐比检测对于早期肾功能病变、年龄>60岁、糖耐量受损(IGT)的老年患者的医学价值。方法随机选择2009年5月到2012年5月,共计260例糖耐量受损的年龄>60岁的老年患者(实验组)资料。另随机选择200位正常人(对照组),检测相应的指标。结果其两组患者检测出的血清胱抑素C与尿白蛋白肌酐比水平指标对比结果差异,具有统计学意义(P<0.05),实验组的阳性检出率中尿微量白蛋白肌酐比和血清胱抑素分别为41.9%和33.7%。而进行了联检的阳性检出率为57.9%。结论血清胱抑素C与尿白蛋白肌酐比联合检测能为IGT患者提供有效的患病依据,及时发现病情并且积极的展开治疗。联合检测对评价老年糖耐量受损患者肾功能具有重要的临床价值。
Objective To evaluate the clinical value of serum cystatin C combined with urinary albumin creatinine in senile patients with early renal dysfunction, age> 60 years and impaired glucose tolerance (IGT) by using the method of joint detection. Methods From May 2009 to May 2012, a total of 260 elderly patients (experimental group) aged> 60 years with impaired glucose tolerance were selected. Another 200 normal subjects (control group) were randomly selected to detect the corresponding indicators. Results The serum cystatin C and urinary albumin creatinine levels were significantly different between the two groups (P <0.05). The positive rate of urine albumin creatinine in the experimental group was significantly higher than that in the experimental group Serum cystatin levels were 41.9% and 33.7%, respectively. The positive detection rate of joint examination was 57.9%. Conclusion The combined detection of serum cystatin C and urinary albumin creatinine can provide an effective basis for the disease in patients with IGT, timely detection of the disease and active treatment. Joint detection of elderly patients with impaired glucose tolerance assessment of renal function has important clinical value.