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白三烯(LTB4)是一个很重要的炎症介质。过去的研究表明,LTB4在炎症时生成增多。本研究发现,中药活血化瘀复方──化解冲剂可抑制腹膜炎大鼠腹腔巨噬细胞生成LTB4,这可能是活血化瘀药抗炎作用的机制之一。
Leukotriene (LTB4) is a very important inflammatory mediator. Past studies have shown that LTB4 produces increased inflammation. This study found that the traditional Chinese medicine Huoxue Huayu Compound ─ ─ Huaxi Granules can inhibit the formation of LTB4 in peritoneal macrophages of rats with peritonitis, which may be one of the mechanisms of anti-inflammatory effects of blood circulation and stasis drugs.