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目的 探讨免疫抑制酸性蛋白 (IAP)与消化系统各种恶性肿瘤的关系。方法 用放射免疫法测定57例消化系统各种恶性肿瘤患者血清IAP水平。结果 各种恶性肿瘤IAP值均不同程度增高 ,尤以胃癌明显 ,各种恶性肿瘤的IAP阳性率为50.00 %～85.71% ,各种恶性肿瘤平均IAP值和IAP阳性率均高于慢性胃炎和正常对照 (均P<0.01) ,慢性胃炎患者和正常对照的IAP值与IAP阳性率差异无显著性意义 (均P>0.05)。结论 IAP可作为一些恶性肿瘤的肿瘤标记之一
Objective To investigate the relationship between immunosuppressive acidic protein (IAP) and various malignant tumors in the digestive system. Methods Radioimmunoassay was used to measure serum IAP levels in 57 patients with various malignant tumors of the digestive system. Results The IAP values of various malignant tumors increased to varying degrees, especially in gastric cancer. The IAP positive rate of various malignant tumors was 50.00% to 85.71%. The average IAP and IAP positive rate of various malignant tumors were higher than that of chronic gastritis and normal. Control (all P <0.01), there was no significant difference between IAP and IAP positive rate in patients with chronic gastritis and normal controls (all P> 0.05). Conclusion IAP can be used as a tumor marker for some malignant tumors