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[目的]分析自贡市HIV感染者/AIDS病人免疫学功能状况,为针对性治疗提供依据。[方法]应用FACSCalibur流式细胞仪,采用Mulitest检测分析软件进行三色检测。[结果]HIV感染者及AIDS患者的CD4+淋巴细胞和CD4+/CD8+比值均明显低于健康人群(P﹤0.01);HIV感染者CD8+T淋巴细胞明显高于健康人群和AIDS患者;HIV感染者中CD4淋巴细胞数200～300/mm3者9例(19.6%,9/46),301～500者22例(43.5%,20/46),﹥500者17例(36.9%,17/46)。CD4淋巴细胞数将随病程进展不断下降。[结论]HIV感染者CD4+细胞降低明显低于正常人水平;有9例HIV感染者CD4+细胞数已降低至200～300/mm3,其中4例已出现了一些临床症状,存在着发展为病人可能,对于此类感染者应作为关爱和治疗的对象。
[Objective] To analyze the immunological status of HIV / AIDS patients in Zigong and provide the basis for targeted therapy. [Method] The FACSCalibur flow cytometry was used to detect the trichromatic by Mulitest detection and analysis software. [Results] The ratio of CD4 + lymphocytes and CD4 + / CD8 + in HIV infected persons and AIDS patients were significantly lower than those in healthy people (P <0.01). The CD8 + T lymphocytes in HIV-infected patients were significantly higher than those in healthy people and AIDS patients. 9 cases (19.6%, 9/46) with CD4 ~ + T lymphocyte count of 200 ~ 300 / mm3, 22 cases (43.5%, 20/46) with 301 ~ 500 cases and 17 cases (36.9%, 17/46) . CD4 lymphocyte number will continue to decline with the progress of the disease. [Conclusion] The CD4 + cells in HIV-infected people decreased significantly lower than that in normal people. The number of CD4 + cells in 9 HIV-infected people was reduced to 200-300 / mm3, of which 4 cases had some clinical symptoms, , For such infected persons should be used as the object of care and treatment.