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近年来,已充分肯定了扩张阻力血管、降低后负荷及有正性肌力作用的药物在治疗充血性心力衰竭中的价值。晚近一些资料表明,氨吡啶酮小剂量有正性肌力作用,大剂量还能扩张血管。它对于已应用毛地黄、利尿剂和血管扩张剂无效的顽固性心力衰竭患者仍有治疗效果,因而,被认为是很有希望的治疗心力衰竭的新药。氨啶酮吡是一种双吡啶衍生物,其化学结构式为:
In recent years, has fully affirmed the expansion of resistance blood vessels, reduce the load and positive inotropic effect of the drug in the treatment of congestive heart failure. Some recent data show that small doses of amiloride positive inotropic effect, high doses can also dilate blood vessels. It is still effective in patients with refractory heart failure who have been treated with ghrelin, diuretics and vasodilators and is therefore considered as a promising new drug for the treatment of heart failure. Pyridoxine is a bipyridine derivative, its chemical formula is: