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目的 探讨在妊娠糖尿病 (GDM )治疗中胰岛素、饮食以及开始治疗时间早晚对围生儿预后的影响。方法 选择诊断为妊娠糖尿病者 10 9例 ,其中采用饮食加胰岛素治疗 2 2例 ,单纯饮食控制 87例。单纯饮食控制的87例又分为 34周前开始饮食控制组 6 0例 ,34周后开始饮食控制组 2 7例。结果 治疗前后孕妇血糖下降程度 ,单纯饮食控制组低于应用胰岛素组 ,差异显著 (P <0 0 5 )。围生儿结局显示 :巨大儿发生率、红细胞增多症发生率三组为 34周后饮食控制组 >34周前饮食控制组 >胰岛素治疗组。结论 GDM要早诊断、早治疗 ,尤其是应用胰岛素正规治疗对降低围生儿病率、巨大儿发生率以及控制孕妇血糖水平有重要意义
Objective To investigate the effect of insulin, diet, and the timing of the initiation of treatment on the prognosis of perinatal infants in gestational diabetes mellitus (GDM). Methods Nine hundred and nine patients diagnosed with gestational diabetes mellitus were selected. Among them, 22 cases were treated with diet plus insulin and 87 cases were controlled by simple diet. 87 cases of simple diet control were divided into 34 cases before diet control group 60 cases, 34 weeks after the start of diet control group 27 cases. Results The level of blood glucose in pregnant women before and after treatment was significantly lower than that in the control group (P <0.05). Perinatal outcome showed that the incidence of macrosomia and polycythemia in three groups was 34 weeks after the diet control group> 34 weeks before the diet control group> insulin treatment group. Conclusions Early diagnosis and early treatment of GDM, especially regular insulin therapy, are of great importance in reducing the incidence of perinatal morbidity, the incidence of macrosomia and the control of blood glucose level in pregnant women